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The evidence from EAE models is striking
Initial treatment for patients with neurological involvement follows British National Formulary (BNF) guidance: Hydroxocobalamin 1 mg intramuscularly on alternate days for approximately 2-3 weeks (or until no further improvement) Maintenance therapy then consists of hydroxocobalamin 1 mg intramuscularly every two months Hydroxocobalamin is preferred over cyanocobalamin in the UK due to superior retention and fewer injections required
Safe administration under the guidance of a healthcare professional ensures optimal effectiveness along with routine monitoring to preclude potential complications or adverse effects
Protocol length varies based on injury severity
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